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KMID : 0357920050390060428
Korean Journal of Pathology
2005 Volume.39 No. 6 p.428 ~ p.432
Gangliocytic Paraganglioma
Kim Joon-Mee

Choi Suk-Jin
Kim Lucia
Han Jee-Young
Chu Young-Chae
Park In-Suh
Kim Hyung-Gil
Choi Sun-Keun
Abstract
Gangliocytic paraganglioma (GP) is a rare benign tumor that is usually seen in the duodenum. It shows unique histologic features that are composed of a carcinoid or paraganglioma-like appearance, ganglion cells, and Schwann cells. The common presenting symptoms are abdominal pain, gastrointestinal bleeding and obstruction. The lesion can sometimes be asymptomatic and they are discovered incidentally. We experienced a case of incidentally found GP in a 73 year-old-man who had a colon cancer with liver metastasis. During the preoperative workup, a submucosal tumor was found in the duodenal papilla. The frozen diagnosis of the duodenal mass was GP, which was confirmed by the permanent sections and immunohistochemical staining. Pathologists should be alert to recognize and diagnose this rare, but benign disease, especially in the patient suffering with gastrointestinal cancer.
KEYWORD
Gangliocytic paraganglioma, Carcinoid, Paraganglioma, Duodenal neoplasm, Immunohistochemistry
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